Malegra DXT Plus is a medication that is used to treat two common sexual disorders in men: erectile dysfunction (ED) and premature ejaculation (PE). It is a combination drug that contains two active ingredients: Sildenafil citrate and Duloxetine. Sildenafil citrate is a phosphodiesterase type 5 (PDE5) inhibitor, which means it helps increase blood flow to the penis, resulting in improved erectile function. It is the same active ingredient found in the popular ED medication Viagra. Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) that is primarily used to treat depression and anxiety disorders. In the context of Malegra DXT Plus, Duloxetine is used to delay ejaculation and improve control over ejaculation, thereby helping to address premature ejaculation.