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Tapentadol is a centrally acting analgesic medication used for the management of moderate to severe pain. It is classified as an opioid analgesic, but it also has additional mechanisms of action beyond traditional opioids.
Tapentadol works by binding to mu-opioid receptors in the central nervous system, similar to traditional opioids. However, it also inhibits the reuptake of norepinephrine, a neurotransmitter involved in pain modulation. This dual mechanism of action distinguishes tapentadol from other opioids and may contribute to its efficacy in managing pain.
Tapentadol is prescribed for the treatment of acute and chronic pain conditions where other pain medications are inadequate. It is commonly used for conditions such as neuropathic pain (nerve pain), chronic back pain, osteoarthritis pain, and pain associated with cancer or surgery.