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Tapentadol is a centrally acting opioid analgesic used for the management of moderate to severe pain. It works by binding to mu-opioid receptors in the central nervous system to produce analgesia. Unlike some other opioids, tapentadol also inhibits the reuptake of norepinephrine, which may contribute to its analgesic effects.

Tapentadol is indicated for the relief of moderate to severe acute pain or chronic pain in adults. It is available in immediate-release (IR) and extended-release (ER) formulations. The immediate-release formulation is typically used for acute pain management, while the extended-release formulation provides around-the-clock pain relief for chronic pain conditions.