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Ambien (or Zolpidem) is among the most extensively studied and clinically proven pharmaceutical preparations used for the management of insomnia and sleep onset difficulties. This drug was developed in order to act on GABA receptors of the brain, helping patients to calm the excessive activity of their neurons and to initiate falling asleep. Its accuracy in terms of regulation of sleep-wake cycle along with fast effect makes this drug very popular among medical practitioners and patients.

The first point of Zolpidem’s action is its selective effect on GABA-A receptor subtypes that are responsible for sedative effect but not muscle relaxation or anti-anxiety effects. Such selectivity of Zolpidem ensures sleep promoting effect while maintaining natural sleep pattern. Thus, patients can get restorative sleep cycles without the suppression of deep sleep or REM phases.

Numerous clinical trials have proven the effectiveness of this medication in terms of reduction of sleep latency – the time needed to fall asleep. Moreover, total sleep time is increased in such patients and nighttime awakenings become less frequent.

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