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Klonopin can have interaction with different medicines, potentially increasing or reducing their outcomes. It's vital to tell your healthcare provider approximately all medicinal drugs, dietary supplements, and herbal merchandise you take before beginning Klonopin. Common drug interactions consist of interactions with other significant anxious device depressants (e.G., alcohol, opioids, positive antidepressants) and medications that have an effect on liver enzyme interest (e.G., some antifungal medicines, positive antibiotics).